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(News Article):High-Dose Vitamin C Therapy Proven Effective
January 20, 2020
12:54 am
Richard Daystrom PhD
Livermore, CA.
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Orthomolecular Medicine News Service, January 5, 2010

High-Dose Vitamin C Therapy Proven Effective

"My doctor doesn't believe in vitamins." Since when is medicine based on belief?


(OMNS, January 5, 2010) The medical literature has virtually ignored 75 years of physician reports and laboratory and clinical studies on successful high-dose vitamin C therapy. Effective doses are high doses, often 1,000 times more than the US Recommended Dietary Allowance (RDA) or Daily Reference Intake (DRI).

It is a cornerstone of medical science that dose affects treatment outcome. This premise is accepted with pharmaceutical drug therapy, but not with vitamin therapy. Most unsuccessful vitamin C research has used inadequate, low doses. Low doses do not get clinical results.

Investigators using vitamin C in high doses have consistently reported excellent results. High doses were advocated almost immediately after ascorbic acid was isolated by Albert Szent-Gyorgyi, M.D. (1893-1986). Notable early medical pioneers of high-dose vitamin C (ascorbate) therapy are Claus Washington Jungeblut, M.D. (1898-1976); William J. McCormick, M.D. (1880-1968); and Frederick R. Klenner, M.D. (1907-1984). More recently, important work has been published by Hugh D. Riordan, M.D. (1932-2005) and Robert F. Cathcart III, M.D. (1932-2007).

It Was 75 Years Ago Today

Dr. Jungeblut, Professor of Bacteriology at Columbia University, first published on vitamin C as prevention and treatment for polio, in 1935. (1) Also, in 1935, Jungeblut showed that vitamin C inactivated diphtheria toxin. (2) By 1937, Jungeblut demonstrated that ascorbate inactivated tetanus toxin. (3) Between 1943 and 1947, Dr. Klenner, a specialist in diseases of the chest, cured 41 cases of viral pneumonia with vitamin C. By 1946, Dr. McCormick showed how vitamin C prevents and also cures kidney stones; by 1957, how it fights cardiovascular disease.

Beginning in the 1960s, Dr. Cathcart used large doses of vitamin C to treat pneumonia, hepatitis, and eventually AIDS. For more than three decades, beginning in 1975, Dr. Riordan and his team have successfully used large doses of intravenous vitamin C against cancer. The use of doses of tens of thousands of milligrams of vitamin C per day may be the most unacknowledged successful research in medicine.

Heard this one before? "If vitamin C was that good, doctors would tell their patients to take a lot of it." It is surprising how many physicians have done precisely that. What's that? Your doctor still doesn't?

Why? Decades of physicians' reports and controlled studies support the use of very large doses of vitamin C.



(1) Jungeblut CW. Inactivation of poliomyelitis virus by crystalline vitamin C (ascorbic acid). J Exper Med 1935. 62:317-321.

(2) Jungeblut CW, Zwemer RL. Inactivation of diphtheria toxin in vivo and in vitro by crystalline vitamin C (ascorbic acid). Proc Soc Exper Biol Med 1935; 32:1229-34.

(3) Jungeblut CW. Inactivation of tetanus toxin by crystalline vitamin C (l-ascorbic acid). J Immunol 1937;33:203-214.


For More Information About:

Dr. CW Jungeblut: Claus Washington Jungeblut, M.D.: Polio pioneer; ascorbate advocate. J Orthomolecular Med, 2006. Vol 21, No 2, p 102-106. http://www.doctoryourself.com/.....eblut.html

In addition to (1) above, Dr. Jungeblut's other polio papers include:

Jungeblut CW. Vitamin C therapy and prophylaxis in experimental poliomyelitis. J Exp Med, 1937. 65: 127-146.

Jungeblut CW. Further observations on vitamin C therapy in experimental poliomyelitis. J Exper Med, 1937. 66: 459-477.

Jungeblut CW, Feiner RR. Vitamin C content of monkey tissues in experimental poliomyelitis. J Exper Med, 1937. 66: 479-491.

Jungeblut CW. A further contribution to vitamin C therapy in experimental poliomyelitis. J Exper Med, 1939. 70:315-332.

Jungeblut's research published in the Journal of Experimental Medicine is available for free access at http://www.jem.org/contents-by.....te.0.shtml

Dr. FR Klenner: Hidden in plain sight: the pioneering work of Frederick Robert Klenner, M.D. J Orthomolecular Med, 2007. Vol 22, No 1, p 31-38. http://www.doctoryourself.com/.....erbio.html and http://orthomolecular.org/hof/.....enner.html

Dr. WJ McCormick: The pioneering work of William J. McCormick, M.D. J Orthomolecular Med, 2003. Vol 18, No 2, p 93-96. http://www.doctoryourself.com/.....rmick.html and http://orthomolecular.org/hof/.....rmick.html

Dr. RF Cathcart: http://orthomolecular.org/hof/.....hcart.html; http://www.doctoryourself.com/.....ation.html and http://www.doctoryourself.com/.....hcart.html

Dr. HD Riordan: http://orthomolecular.org/hof/.....ordan.html; http://orthomolecular.org/reso.....1n09.shtml; http://www.doctoryourself.com/.....rdan1.html and http://www.doctoryourself.com/.....ordan.html

Nutritional Medicine is Orthomolecular Medicine

Orthomolecular medicine uses safe, effective nutritional therapy to fight illness. For more information: http://www.orthomolecular.org

The peer-reviewed Orthomolecular Medicine News Service is a non-profit and non-commercial informational resource.

Editorial Review Board:


  1. Carolyn Dean, M.D., N.D.
  2. Damien Downing, M.D.
  3. Michael Gonzalez, D.Sc., Ph.D.
  4. Steve Hickey, Ph.D.
  5. James A. Jackson, PhD
  6. Bo H. Jonsson, MD, Ph.D
  7. Thomas Levy, M.D., J.D.
  8. Jorge R. Miranda-Massari, Pharm.D.
  9. Erik Paterson, M.D.
  10. Gert E. Shuitemaker, Ph.D.


Andrew W. Saul, Ph.D., Editor and contact person. Email: omns@orthomolecular.org

To Subscribe at no charge: http://www.orthomolecular.org/.....cribe.html

W. O. Belfield, Jr.

January 22, 2020
2:38 pm
Straight Zeke the Geek
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I've been considering this since you posted it here.  Why not?

I use to take Niacin occasionally for my blood but haven't for years.  My new kick is Fenugreek, another wonder herb that does so many things that its difficult to believe it isn't available as widely as Vitamin C tablets.

Thanks for the article.

Aliens, traitors and mortal enemies would oppose me and attack me but not my loved ones, my family, my countrymen or my allies.

March 20, 2020
10:48 am
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March 20, 2020
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Hello Dr. Richard, thanks for sharing an article on High-Dose Vitamin C Therapy. As we all know that these days everyone is afraid of the COVID-19. In my country, there are 200 positive cases and 5 out of 200 is in my city which makes me more afraid. Everything over here like colleges, schools, malls, clubs, gym, office is closed till 31 March. I also staying at home. I was searching for something regarding COVID-19 online and while searching, I have found that taking vitamin C can keep us safe from that COVID-19. So, I want to make sure that it is true or not. I think you can help me in finding my answer. By the way, if you want to read developmental psychology research paper topics online then you can visit https://topicsmill.com/researc.....er-topics/ website to read those topics. You can also find other research paper topics on that website. It is a very useful website and also has great reviews.

March 20, 2020
11:13 pm
Richard Daystrom PhD
Livermore, CA.
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December 19, 2018
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Hello Ingrid:

I am a strong proponent of ascorbic acid (Vitamin C) because it is a substance that is throughout nature. Without ascorbic acid life would cease to exist on this planet. There are three species of animals that cannot synthesize Ascorbic acid ( the late Irwin Stone PhD the person who turned on the two time Nobel laureate Linus Pauling PhD to ascorbic acid preferred the term ascorbic acid over vitamin C) Homo sapiens are one of them. Why not take a substance that our bodies should be making but isn't!. Also I would recommend checking out this website http://www.doctoryourself.com/


-R. Daystrom-

W. O. Belfield, Jr.

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