I think as far as art, HR Giger is one of my favorites. Though there are tons of great artists in the comic book industry, but some don't see that as legitimate art. However, in that case I think one of my favorites is Salvador Larroca, Bernie Wrightson or Terry Dodson (especially when his art is inked by his wife Rachel. They make a great team.
"To alcohol, the cause of and solution to all of life's problems." -- Homer Simpson
"You get what everyone gets. You get a lifetime." -- Death (Sandman)