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A Further Look at the Biosynthesis of Ascorbic Acid on Evolution and Natural Selection.
July 1, 2016
8:24 pm
Forum Posts: 102
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January 28, 2015
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A Further Look at the Biosynthesis of Ascorbic Acid on Evolution and Natural Selection: Pre-Cargo Cult Phenomena

  “Science is a search for the explanation of how things work, not a search for something called “proof” that by direct implication, prevents questioning.”

                                                                                         James Le Fanu, M.D

“Discovery consists of seeing what everybody has seen and thinking what nobody has thought,”                                                          

                                                                                         Dr. Szent-Gyorgyi’s


    The biosynthesis of ascorbic acid is fascinating. The first three biochemical pathways (called the “trinity”) gives ascorbic the property of being “somewhat unstable and transient” as described by Irwin Stone PhD. Pathway #4 is called the “life-force donor.”  When it is functional, planetary life flourishes.

    The Genetics of Vitamin C Loss in Vertebrates, authored by Guy Drouin, Jean-Remi Godin & Benoit Page, provides the best well-argued and thoughtful explanation for the loss of C6H8O6 in vertebrates. It is hypothesized that biochemical pathways #1 through #3 are susceptible to multiple mutations which creates a non-functional psuedogene which will turn off the GLO enzyme, and will affect other biochemical pathways. It has been speculated that pathway #4 is deactivated by a transitional point mutation. When pathways #1 through #3 are non-functioning in having the inability to synthesize gluconolactonase it; “would not only affect the formation of L-gulono-1, 4 lactone, but would also affect caprolactam degradation and the pentose phosphate pathway, among others. Compared to other genes, The GLO gene (pathway #4) is therefore predisposed to being lost because it makes a single compound unnecessary for other pathways.”

   Mario C. DeTullio, PhD has some doubt as to how Homo sapiens could have evolved normally without the ability to internally synthesize ascorbic acid. He states the following; “but how can something so crucial for survival be eliminated through the course of evolution? Typically, we expect that positive traits should be retained during evolution, and as vitamin C is beneficial, how would natural selection remove such a crucial biosynthetic capability? Indeed, individuals carrying the mutation(s) in the gene encoding gulonolactone oxidase should have had less chance of surviving and reproducing. However, the opposite occurred, and those who had lost vitamin C biosynthesis survived. How can we explain this apparent paradox? ”

    The perplexing question is how Darwinian evolution by way of natural selection was able to determine that the best way to deactivate L-gulonolactone oxidase molecule was at the last step in the biochemical synthesis of ascorbic acid (pathway #4). Did evolution arrive at this solution through a process of elimination, or by the luck of the draw? If process of elimination was the evolutionary method of choice, wouldn’t there have been a tremendous number of animals either seriously ill or in a terribly weakened state so that neither one of these groups would have been fortunate enough to produce any viable offspring? If viable offspring were produced they probably would have had a very small breeding population to exchange their genetic material. Inbreeding would have been very common in these scorbutic groups. As a result, extinction would have been the likely outcome for these mammals.

    What if there were small groups of sentient lifeforms, by way of natural selection were able to survive the shutting down of three or four of the biochemical pathways during the biosynthesis of ascorbic acid. Let’s say evolution selected four groups to go through this process of elimination. All four groups are thriving at biochemical pathway #1. Do to cosmic gamma rays Pathway #1 becomes deactivated. One of the four groups becomes extinct. The cause of extinction would be the inability to adapt to changes biochemically, environmentally or both. The remaining three would receive courtesy of natural selection specific biochemical enhancements. The nature of the improvements would be dependent on the specific environments they were adapted to. These positive traits would be successful reproduction and an increase in intelligence.

    Biochemical pathway #2 shuts down. Another group becomes extinct. Two groups remain. Further evolutionary enhancements for these two groups would be continual reproduction and a further increase in intelligence along with a longer lifespan.

    Pathway #3 is deactivated. One of the remaining 2 groups becomes extinct. The last group has reached Pathway #4. The power to control their own fate is the culmination of years adapting to the vagaries of natural selection. In addition to controlling their own destiny these beings have the following enhancements. They have an exceptionally long and healthy life. Reproduction is no longer crucial for the continued existence of the species. If they have had a long evolutionary history of internally synthesizing ascorbic acid, they are now resistant to most diseases. They may possess extraordinary physical strength.  Mental telepathy is a new enhancement. Having an exceptionally high intelligence allows them the power to control their own evolutionary destiny. There evolutionary destiny could possibly exceed the confines of the third dimension.

    The growing preponderance of evidence seems to indicate that Homo sapiens were genetically engineered. The genetically engineered humans skipped over the first three biochemical pathways in the synthesis of ascorbic acid. The leaping over these three pathways did not provide the needed evolutionary upgrades to ensure the continuation of human evolution.

    The cargo cult phenomenon was the only alternative humans had to compensate for the short-cuts taken in their creation. The adoption of the cargo cult phenomena was to provide an environment whereby those who created the human race would eventually be compelled to share their accumulated knowledge with their creation.

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